MOTS-C is a research compound. It is not approved by the FDA or any regulatory body for human use. This article is for educational and informational purposes only. Nothing here constitutes medical advice. Consult a qualified physician before considering any peptide use.
MOTS-C is typically reconstituted with bacteriostatic water (BAC water). The standard dosage of 5-10 mg per week is administered 2-3 times weekly via subcutaneous injection. Use our peptide calculator for exact mixing ratios.
How Do You Reconstitute MOTS-C?
MOTS-C is supplied as a lyophilized (freeze-dried) powder that must be reconstituted before use. Proper reconstitution is critical for accurate dosing and maintaining stability.
This guide covers the step-by-step process for mixing MOTS-C with bacteriostatic water to achieve your target concentration.
What Supplies Do You Need?
To reconstitute MOTS-C, you need: the MOTS-C vial (lyophilized powder), bacteriostatic water (BAC water with 0.9% benzyl alcohol), insulin syringes (typically 1mL/100-unit), alcohol swabs, and a clean workspace.
Important: Always use bacteriostatic water — not sterile water or saline. BAC water's benzyl alcohol prevents bacterial contamination, extending the usable life of reconstituted MOTS-C to 4-6 weeks.
Step-by-Step MOTS-C Reconstitution
Step 1: Clean the vial tops of both the MOTS-C and BAC water with alcohol swabs.
Step 2: Draw the calculated amount of BAC water into an insulin syringe. Use our peptide calculator to determine the exact amount.
Step 3: Insert the needle into the MOTS-C vial at an angle, and let the water run down the side of the glass — never spray directly onto the powder as this can damage the peptide bonds.
Step 4: Gently swirl (do not shake) the vial until the powder is fully dissolved. The solution should be clear.
Step 5: Label the vial with the date and concentration. Store at 2-8°C.
Calculate Your MOTS-C Dose
Use our free peptide dosing calculator to get exact reconstitution math and syringe units for MOTS-C.
Open Calculator →How Do You Dose Reconstituted MOTS-C?
After reconstitution, the standard MOTS-C dose is 5-10 mg per week administered 2-3 times weekly via subcutaneous injection. The number of units on your insulin syringe depends on how much BAC water you added.
Our calculator will tell you exactly how many units to draw for your dose based on your specific reconstitution ratio.
How Do You Store Reconstituted MOTS-C?
Store reconstituted MOTS-C at 2-8°C (standard refrigerator temperature). Use within 4-6 weeks. Keep away from light and temperature fluctuations.
Unreconstituted MOTS-C powder can be stored at -20°C for 12+ months. Once you reconstitute it, the clock starts.
Bottom Line
Reconstituting MOTS-C is straightforward — add BAC water, swirl gently, refrigerate. The key is using the right amount of water for accurate dosing. Use our peptide calculator every time.
Complete Guide
MOTS-c: The Metabolic Mitochondrial Peptide
Related Reading
- MOTS-C Dosage Guide
- MOTS-C Benefits
- MOTS-C Side Effects
- MOTS-C Stacking Guide
- MOTS-C Cycle Guide
- MOTS-C Research
Research-Grade Sourcing
If you're going to research MOTS-C, source matters. These are the suppliers WolveStack has vetted for purity and third-party testing.
Frequently Asked Questions
What is MOTS-C?
MOTS-C (Mitochondrial ORF of the 12S rRNA Type-C) is a Mitochondrial-derived peptide, metabolic regulator. Encoded by the 12S rRNA region of the mitochondrial genome; naturally produced in response to stress, exercise, and aging. It is researched for improved insulin sensitivity, glucose metabolism, fat loss, lean muscle preservation, exercise capacity enhancement, anti-aging, metabolic flexibility.
What is the recommended MOTS-C dosage?
Common dosages: 5-10 mg per week administered 2-3 times weekly via subcutaneous injection. Cycle length: 8-12 weeks with 8-12 week breaks. Half-life: not established in humans. Use our peptide calculator for exact reconstitution math.
What are the side effects of MOTS-C?
Generally well-tolerated. Mild injection site reactions and transient digestive disturbances at higher doses. CB4211 analog showed good tolerability in a 4-week human trial.
Is MOTS-C safe?
MOTS-C has shown a favorable safety profile in research. Not FDA-approved. Listed by FDA as unlawful for compounding. Available as research chemical only. All research should follow appropriate safety protocols.