⚠️ Disclaimer

Semax is a research compound. It is not approved by the FDA or any regulatory body for human use. This article is for educational and informational purposes only. Nothing here constitutes medical advice. Consult a qualified physician before considering any peptide use.

Semax is typically reconstituted with bacteriostatic water (BAC water). The standard dosage of 200-600 mcg daily is administered 2-4 times daily via intranasal spray. Use our peptide calculator for exact mixing ratios.

How Do You Reconstitute Semax?

Semax is supplied as a lyophilized (freeze-dried) powder that must be reconstituted before use. Proper reconstitution is critical for accurate dosing and maintaining stability.

This guide covers the step-by-step process for mixing Semax with bacteriostatic water to achieve your target concentration.

What Supplies Do You Need?

To reconstitute Semax, you need: the Semax vial (lyophilized powder), bacteriostatic water (BAC water with 0.9% benzyl alcohol), insulin syringes (typically 1mL/100-unit), alcohol swabs, and a clean workspace.

Important: Always use bacteriostatic water — not sterile water or saline. BAC water's benzyl alcohol prevents bacterial contamination, extending the usable life of reconstituted Semax to 4-6 weeks.

Step-by-Step Semax Reconstitution

Step 1: Clean the vial tops of both the Semax and BAC water with alcohol swabs.

Step 2: Draw the calculated amount of BAC water into an insulin syringe. Use our peptide calculator to determine the exact amount.

Step 3: Insert the needle into the Semax vial at an angle, and let the water run down the side of the glass — never spray directly onto the powder as this can damage the peptide bonds.

Step 4: Gently swirl (do not shake) the vial until the powder is fully dissolved. The solution should be clear.

Step 5: Label the vial with the date and concentration. Store at 2-8°C.

Calculate Your Semax Dose

Use our free peptide dosing calculator to get exact reconstitution math and syringe units for Semax.

Open Calculator →

How Do You Dose Reconstituted Semax?

After reconstitution, the standard Semax dose is 200-600 mcg daily administered 2-4 times daily via intranasal spray. The number of units on your insulin syringe depends on how much BAC water you added.

Our calculator will tell you exactly how many units to draw for your dose based on your specific reconstitution ratio.

How Do You Store Reconstituted Semax?

Store reconstituted Semax at 2-8°C (standard refrigerator temperature). Use within 4-6 weeks. Keep away from light and temperature fluctuations.

Unreconstituted Semax powder can be stored at -20°C for 12+ months. Once you reconstitute it, the clock starts.

Bottom Line

Reconstituting Semax is straightforward — add BAC water, swirl gently, refrigerate. The key is using the right amount of water for accurate dosing. Use our peptide calculator every time.

Complete Guide

Semax: The Russian Nootropic Peptide

Read the Full Guide →

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Research-Grade Sourcing

If you're going to research Semax, source matters. These are the suppliers WolveStack has vetted for purity and third-party testing.

Ascension → Browse Semax

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Frequently Asked Questions

What is Semax?

Semax (Synthetic ACTH(4-10) analog heptapeptide) is a Neuropeptide, nootropic, ACTH analog. Developed by Russian scientists in the 1980s as a synthetic ACTH fragment analog for neuroprotection in stroke and cognitive decline. It is researched for BDNF elevation, neuroprotection, cognitive enhancement, stroke recovery, memory consolidation.

What is the recommended Semax dosage?

Common dosages: 200-600 mcg daily administered 2-4 times daily via intranasal spray. Cycle length: 5-14 days; repeated cycles with washout. Half-life: not established. Use our peptide calculator for exact reconstitution math.

What are the side effects of Semax?

Nasal irritation (dryness, burning). Nasal cavity discoloration in ~10% of users. Possible increased blood glucose in diabetics. Overall mild adverse effects.

Is Semax safe?

Semax has shown a preliminary safety profile in research. Not FDA-approved. Licensed pharmaceutical in Russia. Available as research chemical in US. All research should follow appropriate safety protocols.