Selank is a research compound. It is not approved by the FDA or any regulatory body for human use. This article is for educational and informational purposes only. Nothing here constitutes medical advice. Consult a qualified physician before considering any peptide use.
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro heptapeptide) is a Nootropic anxiolytic peptide. Developed by the Institute of Molecular Genetics (Russian Academy of Sciences) as a benzodiazepine-like anxiolytic without sedation or dependence. It is researched for anxiety reduction, cognitive enhancement, stress resilience, benzodiazepine-like anxiolysis without dependence. Common dosages range from 75-300 mcg administered 1-3 times daily.
What Is Selank?
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro heptapeptide) is a Nootropic anxiolytic peptide. Developed by the Institute of Molecular Genetics (Russian Academy of Sciences) as a benzodiazepine-like anxiolytic without sedation or dependence. Also known as Selank, tuftsin-derived anxiolytic, it has been studied for its potential effects on anxiety reduction, cognitive enhancement, stress resilience, benzodiazepine-like anxiolysis without dependence.
First anxiolytic peptide achieving benzodiazepine-equivalent action without any dependence, withdrawal, or amnesia — solving the fundamental safety limitation of the entire benzodiazepine drug class. In the research community, Selank has gained attention for its distinctive profile.
How Does Selank Work?
Allosterically modulates GABAA receptors and inhibits enkephalin-degrading enzymes. Influences dopaminergic and serotonergic systems while enhancing GABA-mediated neurotransmission, producing anxiolytic effects comparable to benzodiazepines without receptor downregulation, tolerance, or dependence.
This multi-pathway activity helps explain why Selank shows potential across several different applications.
What Does the Research Say About Selank?
Clinical noninferiority trial in 62 GAD patients showed similar anxiolytic action to medazepam (benzodiazepine). Multiple Russian clinical studies demonstrate efficacy. Evidence base predominantly from Russian institutions.
Researchers should consult the latest peer-reviewed literature for the most current findings.
What Is the Recommended Selank Dosage?
Standard Selank dosing: 75-300 mcg, administered 1-3 times daily via intranasal spray.
Half-life: not established. Cycle length: 5-21 days with washout periods.
Use our peptide dosing calculator for exact reconstitution ratios.
Calculate Your Selank Dose
Use our free peptide dosing calculator to get exact reconstitution math and syringe units for Selank.
Open Calculator →What Are the Side Effects of Selank?
Well-tolerated. Mild nasal irritation at application site. No amnesia, withdrawal, or dependence liability — unlike benzodiazepines.
Selank is not fda-approved. approved in russia (2009) for generalized anxiety disorder. available as research chemical in us.
Can You Stack Selank With Other Peptides?
Pairs with Semax for enhanced cognitive and anxiolytic effects through complementary GABAergic/dopaminergic pathways.
What Is the Bottom Line on Selank?
Selank is a Nootropic anxiolytic peptide researched for anxiety reduction, cognitive enhancement, stress resilience, benzodiazepine-like anxiolysis without dependence. Standard protocols use 75-300 mcg 1-3 times daily for 5-21 days with washout periods.
Source from COA-tested vendors. Read our beginner's guide for more, or use the dosing calculator to plan your protocol.
Complete Guide
Selank: The Anxiolytic Research Peptide
Related Reading
- Selank Dosage Guide
- Selank Benefits
- Selank Side Effects
- Selank Stacking Guide
- Selank Cycle Guide
- Selank Research
Research-Grade Sourcing
If you're going to research Selank, source matters. These are the suppliers WolveStack has vetted for purity and third-party testing.
Frequently Asked Questions
What is Selank?
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro heptapeptide) is a Nootropic anxiolytic peptide. Developed by the Institute of Molecular Genetics (Russian Academy of Sciences) as a benzodiazepine-like anxiolytic without sedation or dependence. It is researched for anxiety reduction, cognitive enhancement, stress resilience, benzodiazepine-like anxiolysis without dependence.
What is the recommended Selank dosage?
Common dosages: 75-300 mcg administered 1-3 times daily via intranasal spray. Cycle length: 5-21 days with washout periods. Half-life: not established. Use our peptide calculator for exact reconstitution math.
What are the side effects of Selank?
Well-tolerated. Mild nasal irritation at application site. No amnesia, withdrawal, or dependence liability — unlike benzodiazepines.
Is Selank safe?
Selank has shown a favorable safety profile in research. Not FDA-approved. Approved in Russia (2009) for generalized anxiety disorder. Available as research chemical in US. All research should follow appropriate safety protocols.