⚠️ Disclaimer

MOTS-C is a research compound. It is not approved by the FDA or any regulatory body for human use. This article is for educational and informational purposes only. Nothing here constitutes medical advice. Consult a qualified physician before considering any peptide use.

Lyophilized (freeze-dried) MOTS-C should be stored at -20°C for long-term stability. Once reconstituted with bacteriostatic water, store at 2-8°C (refrigerated) and use within 4-6 weeks. Never freeze reconstituted peptides.

How Do You Store MOTS-C?

Proper storage is critical for maintaining MOTS-C's potency and safety. As a Mitochondrial-derived peptide, metabolic regulator, MOTS-C is sensitive to heat, light, and moisture — improper storage can render it ineffective or harmful.

How Do You Store Lyophilized MOTS-C?

Unreconstituted (freeze-dried) MOTS-C: Store at -20°C (standard freezer) for maximum shelf life of 12-24+ months. Keep the vial sealed and away from moisture.

Room temperature storage is acceptable for short periods (shipping) but degrades potency over weeks. Refrigerator (2-8°C) storage extends this to several months.

How Do You Store Reconstituted MOTS-C?

After mixing with bacteriostatic water: Store at 2-8°C (standard refrigerator). Use within 4-6 weeks for optimal potency.

Never freeze reconstituted MOTS-C. Freezing and thawing damages the peptide structure. The bacteriostatic water's benzyl alcohol preservative is what allows the 4-6 week window — sterile water would give you only days.

Keep the vial upright and away from the refrigerator door (temperature fluctuations from opening/closing).

How Do You Know if MOTS-C Has Gone Bad?

Reconstituted MOTS-C should be clear and colorless. If you see cloudiness, particles, or discoloration — discard it. These indicate bacterial contamination or peptide degradation.

If stored properly, degradation is gradual and may not be visually apparent. This is why the 4-6 week window for reconstituted peptides exists.

Can You Travel With MOTS-C?

Lyophilized MOTS-C can be shipped with cold packs and insulation. For short trips, a small cooler bag with an ice pack maintains adequate temperature.

Reconstituted MOTS-C is more temperature-sensitive and should be kept refrigerated during travel if possible.

Bottom Line on MOTS-C Storage

Freeze-dried: -20°C, sealed, 12+ months. Reconstituted: 2-8°C, use within 4-6 weeks, never freeze. Source from vendors who ship with proper cold-chain packaging.

Complete Guide

MOTS-c: The Metabolic Mitochondrial Peptide

Read the Full Guide →

Related Reading

Calculate Your MOTS-C Dose

Use our free peptide dosing calculator to get exact reconstitution math and syringe units for MOTS-C.

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Research-Grade Sourcing

If you're going to research MOTS-C, source matters. These are the suppliers WolveStack has vetted for purity and third-party testing.

Ascension → Browse MOTS-C

Particle → Browse MOTS-C

Limitless → Browse MOTS-C

Frequently Asked Questions

What is MOTS-C?

MOTS-C (Mitochondrial ORF of the 12S rRNA Type-C) is a Mitochondrial-derived peptide, metabolic regulator. Encoded by the 12S rRNA region of the mitochondrial genome; naturally produced in response to stress, exercise, and aging. It is researched for improved insulin sensitivity, glucose metabolism, fat loss, lean muscle preservation, exercise capacity enhancement, anti-aging, metabolic flexibility.

What is the recommended MOTS-C dosage?

Common dosages: 5-10 mg per week administered 2-3 times weekly via subcutaneous injection. Cycle length: 8-12 weeks with 8-12 week breaks. Half-life: not established in humans. Use our peptide calculator for exact reconstitution math.

What are the side effects of MOTS-C?

Generally well-tolerated. Mild injection site reactions and transient digestive disturbances at higher doses. CB4211 analog showed good tolerability in a 4-week human trial.

Is MOTS-C safe?

MOTS-C has shown a favorable safety profile in research. Not FDA-approved. Listed by FDA as unlawful for compounding. Available as research chemical only. All research should follow appropriate safety protocols.